1Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, Washington

2Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina

3Department of Epidemiology and Welch Center for Prevention, Epidemiology, & Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland

4Welch Center for Prevention, Epidemiology, & Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland

5Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina

6Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts

7Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts

8Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina

9School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas

10Department of Genetics, Stanford University School of Medicine, Stanford, California

11Department of Genetics, University of North Carolina, Chapel Hill, North Carolina

12Center for Global Cardiometabolic Health, Departments of Epidemiology, Medicine, and Surgery, Brown University, Providence, Rhode Island

13Brigham and Women's Hospital, Harvard Medical School, Harvard T.H. Chan School of Public Health, Boston, Massachusetts

14Division of Biostatistics, Institute for Health and Equity, and Cancer Center, Medical College of Wisconsin, Milwaukee, Wisconsin

15Division of Pulmonary, Allergy and Critical Care, Department of Medicine, Duke University Medical Center, Durham, North Carolina

16Division of Precision Medicine, New York University Grossman School of Medicine, New York, New York

17Department of Epidemiology, University of Washington, Seattle, Washington

Correspondence: Dr. Alex P. Reiner, Department of Epidemiology, University of Washington, 1959 NE Pacific Street, Health Sciences Building, F-262, Box 357236, Seattle, WA 98195. Email: [email protected]

L.M.R. and A.P.R. contributed equally to this work.

See related editorial, “Sickle Cell Trait and Circulating Proteome,” on pages 1391–1392.