Weatherall DJ. The challenge of haemoglobinopathies in resource-poor countries. Br J Haematol. 2011;154(6):736–44.
Huang H, Chen M, Chen L, Zhang M, Wang Y, Lin N, et al. Prenatal diagnosis of Thalassemia in 695 pedigrees from southeastern China: a 10-year follow‐up study. J Clin Lab Anal. 2021;35(10):e23982.
Article CAS PubMed PubMed Central Google Scholar
Alsaeed ES, Farhat GN, Assiri AM, Memish Z, Ahmed EM, Saeedi MY, et al. Distribution of hemoglobinopathy disorders in Saudi Arabia based on data from the premarital screening and genetic counseling program, 2011–2015. J Epidemiol Glob Health. 2018;7(Suppl 1):41–S7.
Memish ZA, Owaidah TM, Saeedi MY. Marked regional variations in the prevalence of sickle cell Disease and beta-thalassemia in Saudi Arabia: findings from the premarital screening and genetic counseling program. J Epidemiol Glob Health. 2011;1(1):61–8.
Article PubMed PubMed Central Google Scholar
Olwi DI, Merdad LA, Ramadan EK. Thalassemia: a prevalent Disease yet unknown term among college students in Saudi Arabia. J Community Genet. 2018;9(3):277–82.
Moustafa AZ, EI RAA, RA Q, ZS Q. The prevalence of hemoglobin abnormality in the premarital screening Saudi population in Makkah city in a cross-sectional study. SMHJ [Internet]. 2022;2(1):17–25.
Dehbozorgian J, Moghadam M, Daryanoush S, Haghpanah S, Imani fard J, Aramesh A, et al. Distribution of alpha-thalassemia mutations in Iranian population. Hematology. 2015;20(6):359–62.
Article CAS PubMed Google Scholar
Borgio JF, AbdulAzeez S, Al-Nafie AN, Naserullah ZA, Al-Jarrash S, Al-Madan MS, et al. A novel HBA2 gene conversion in cis or trans: alpha12 allele in a Saudi population. Blood Cells Mol Dis. 2014;53(4):199–203.
Article CAS PubMed Google Scholar
Borgio JF. Molecular nature of alpha-globin genes in the Saudi population. Saudi Med J. 2015;36(11):1271–6.
Article PubMed PubMed Central Google Scholar
Qiu Q-W, Wu D-D, Yu L-H, Yan T-Z, Zhang W, Li Z-T, et al. Evidence of recent natural selection on the southeast Asian deletion (--SEA) causing α-thalassemia in South China. BMC Evol Biol. 2013;13(1):1–10.
Munkongdee T, Vattanaviboon P, Thummarati P, Sewamart P, Winichagoon P, Fucharoen S, et al. Rapid diagnosis of α-Thalassemia by melting curve analysis. J Mol Diagn. 2010;12(3):354–8.
Article CAS PubMed PubMed Central Google Scholar
Vichinsky EP. Clinical manifestations of alpha-thalassemia. Cold Spring Harb Perspect Med. 2013;3(5):a011742.
Article PubMed PubMed Central Google Scholar
Ataulfo Gonzalez F, Blazquez C, Ropero P, Briceno O, Alaez C, Polo M, et al. [Association of hemoglobinopathy and alpha thalassemia. Study of 45 patients]. Med Clin (Barc). 2005;124(19):726–9.
Lithanatudom P, Khampan P, Smith DR, Svasti S, Fucharoen S, Kangwanpong D, et al. The prevalence of alpha-thalassemia amongst Tai and Mon-Khmer ethnic groups residing in northern Thailand: a population-based study. Hematology. 2016;21(8):480–5.
Article CAS PubMed Google Scholar
Velasco-Rodriguez D, Blas C, Alonso-Dominguez JM, Vega G, Soto C, Garcia-Raso A et al. Cut-off values of hematologic parameters to predict the number of alpha genes deleted in subjects with Deletional Alpha Thalassemia. Int J Mol Sci. 2017;18(12).
Pornprasert S, Salaeh NA, Tookjai M, Punyamung M, Pongpunyayuen P, Treesuwan K. Hematological Analysis in Thai samples with Deletional and Nondeletional HbH Diseases. Lab Med. 2018;49(2):154–9.
Chui DH, Fucharoen S, Chan V. Hemoglobin H Disease: not necessarily a benign disorder. Blood. 2003.
Origa R, Sollaino M, Giagu N, Barella S, Campus S, Mandas C, et al. Clinical and molecular analysis of haemoglobin H Disease in Sardinia: haematological, obstetric and cardiac aspects in patients with different genotypes. Br J Haematol. 2007;136(2):326–32.
Article CAS PubMed Google Scholar
Kanavakis E, Papassotiriou I, Karagiorga M, Vrettou C, Metaxotou-Mavrommati A, Stamoulakatou A, et al. Phenotypic and molecular diversity of haemoglobin H Disease: a Greek experience. Br J Haematol. 2000;111(3):915–23.
Article CAS PubMed Google Scholar
Bajwa H, Basit H. Thalassemia. StatPearls. Treasure Island (FL) ineligible companies. Disclosure: Hajira Basit declares no relevant financial relationships with ineligible companies.2023.
Keser I, Mercan T, Bilgen T, KÜPESİZ O, Arikan Y, Canatan D. Investigation of alpha globin gene mutations by complementary methods in Antalya. Eastern J Med. 2021;26(1).
Puehringer H, Najmabadi H, Law HY, Krugluger W, Viprakasit V, Pissard S, et al. Validation of a reverse-hybridization StripAssay for the simultaneous analysis of common alpha-thalassemia point mutations and deletions. Clin Chem Lab Med. 2007;45(5):605–10.
Article CAS PubMed Google Scholar
Sabath DE. Molecular diagnosis of Thalassemias and hemoglobinopathies: an ACLPS critical review. Am J Clin Pathol. 2017;148(1):6–15.
Article CAS PubMed Google Scholar
Hellani A, Fadel E, El-Sadadi S, El-Sweilam H, El-Dawood A, Abu-Amero KK. Molecular spectrum of α-thalassemia mutations in microcytic hypochromic anemia patients from Saudi Arabia. Genetic Test Mol Biomarkers. 2009;13(2):219–21.
Borgio JF, Abdulazeez S, Almandil NB, Naserullah ZA, Al–Jarrash S, Al–Suliman AM, et al. The–α3. 7 deletion in α–globin genes increases the concentration of fetal hemoglobin and hemoglobin A2 in a Saudi Arabian population. Mol Med Rep. 2018;17(1):1879–84.
Akhtar MS, Qaw F, Borgio JF, Albuali W, Suliman A, Nasserullah Z, et al. Spectrum of alpha-thalassemia mutations in transfusion-dependent beta-thalassemia patients from the Eastern Province of Saudi Arabia. Hemoglobin. 2013;37(1):65–73.
Article CAS PubMed Google Scholar
Attallahm S, Alhadad M, Alqarni W, Filfilan D, Zaharani A, Alharby A, MOLECULAR SPECTRUM OF ALPHA THALASSEMIA MUTATIONS IN THE WESTERN PROVINCE OF SAUDI ARABIA AND RECOMMENDATION FOR PREMARITAL SCREENING. Hemasphere. 2023; 8;(7).
Moradi K, Aznab M, Azimi A, Biglari M, Shafieenia S, Alibakhshi R. α-thalassemia mutations in Ilam Province, West Iran. Hemoglobin. 2022;46(3):147–52.
Article CAS PubMed Google Scholar
Prior J, Bittles A, Erber W. A community profile of alpha thalassaemia in Western Australia. Public Health Genomics. 2004;7(4):211–5.
Anselmo FC, Ferreira NS, Mota AJd, Gonçalves MS, Albuquerque SRL, Fraiji NA et al. Deletional alpha-thalassemia alleles in amazon blood donors. Advances in Hematology. 2020;2020.
Adekile A, Sukumaran J, Thomas D, D’Souza T, Haider M. Alpha Thalassemia genotypes in Kuwait. BMC Med Genet. 2020;21(1):1–5.
Ghoush MWA. Subtypes of alpha thalassemia diagnosed at a Medical Center in Jordan. TSK Koruyucu Hekimlik Bülteni. 2008;7(5):373–6.
Jassim N, Al-Arrayed S, Gerard N, Al-Mukharraq H, Al-Ajami A, Ducrocoq R, et al. Molecular basis of α-thalassemia in Bahrain. Bahrain Med Bull. 2001;23(1):3–7.
Al Moamen NJ, Thabet A, Mahdi F, Newton H, Salman E. Various α-thalassemia genotype combinations of the saudi-type polyadenylation signal mutation (αT-Saudiα) in the population of Bahrain: an update of genotype-phenotype analyses. Hemoglobin. 2018;42(3):166–70.
Article CAS PubMed Google Scholar
El-Kalla S, Baysal E. α-thalassemia in the United Arab Emirates. Acta Haematol. 1998;100(1):49–53.
Article CAS PubMed Google Scholar
Al-Awamy BH. Thalassemia syndromes in Saudi Arabia. Saudi Med J. 2000;21(1):8–17.
ABDULLA ALHARBY M, ATTALLAH S, WALAA AQ, MARWA AH, FILFILAN D. Characterization of the Molecular Spectrum of a-Thalassemia mutations in the Western Province of Saudi Arabia and recommendation for Premarital Screening. Med J Cairo Univ. 2022;90(12):2123–9.
Baysal E. α-Thalassemia syndromes in the United Arab Emirates. Hemoglobin. 2011;35(5–6):574–80.
Article CAS PubMed Google Scholar
Farra C, Badra R, Fares F, Muwakkit S, Dbaibo G, Dabbous I, et al. Alpha thalassemia allelic frequency in Lebanon. Pediatr Blood Cancer. 2015;62(1):120–2.
Article CAS PubMed Google Scholar
Kyriakou A, Savva SC, Savvides I, Pangalou E, Ioannou YS, Christou S, et al. Gender differences in the prevalence and severity of bone Disease in Thalassaemia. Pediatr Endocrinol Rev. 2008;6(Suppl 1):116–22.
Toumba M, Skordis N. Osteoporosis syndrome in Thalassaemia major: an overview. J Osteoporos. 2010;2010:537673.
Article PubMed PubMed Central Google Scholar
Ishikawa I, Maeda K, Nakai S, Kawaguchi Y. Gender difference in the mean age at the induction of hemodialysis in patients with autosomal dominant polycystic Kidney Disease. Am J Kidney Dis. 2000;35(6):1072–5.
Article CAS PubMed Google Scholar
Woldu DO, Haile ZT. Gender roles and perceptions of Malaria risk in agricultural communities of Mwea Division in Central Kenya. Women Health. 2015;55(2):227–43.
Marsella M, Pepe A, Borgna-Pignatti C. Better survival and less cardiac morbidity in female patients with Thalassemia major: a review of the literature. Ann N Y Acad Sci. 2010;1202:129–33.
Husna N, Sanka I, Al Arif A, Putri C, Leonard E, Handayani N. Prevalence and distribution of Thalassemia trait screening. J Med Sci. 2017;49(3):106–13.
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