1Department of Genetics and Biotechnology, College of Life Science, Kyung Hee University, Yongin, South Korea;

2Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA;

3Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA;

4Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA;

5Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA;

6Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA;

7Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Correspondence: Jihye Kim, PhD. E-mail: [email protected].

SUPPLEMENTARY MATERIAL accompanies this paper at https://links.lww.com/AJG/D3