Stovner LJ, Hagen K, Linde M, Steiner TJ. The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates. J Headache Pain. 2022;23:1–17. https://doi.org/10.1186/s10194-022-01402-2.

Article  Google Scholar 

Vukasinovic N, Jolic S, Milosevic V, Zivkovic M, Slankamenac P. EHMTI-0128. Headache as an initial symptom with the patients treated at the intensive care unit of the Clinic of Neurology 1997 – 2013. J Headache Pain. 2014;15:D75. https://doi.org/10.1186/1129-2377-15-S1-D75.

Morad A, Farrokh S, Papangelou A. Pain management in neurocritical care. An update Curr Opin Crit Care. 2018;24:72–9. https://doi.org/10.1097/MCC.0000000000000480.

Article  PubMed  Google Scholar 

Dhakal LP, Harriott AM, Capobianco DJ, Freeman WD. Headache and its approach in today’s neurointensive care unit. Neurocrit Care. 2016;25:320–34. https://doi.org/10.1007/s12028-016-0260-z.

Article  PubMed  Google Scholar 

• Maciel CB, Barlow B, Lucke-Wold B, Gobinathan A, Abu-Mowis Z, Peethala MM, et al. Acute headache management for patients with subarachnoid hemorrhage: an international survey of health care providers. Neurocrit Care. 2023;38:395–406. https://doi.org/10.1007/s12028-022-01571-7. This comprehensive international survey characterizes health care providers diverse practices for management of acute headache in SAH patients.

•• Klavansky D, Wanchoo S, Lin A, Temes RE, Rebeiz T. Predictors of opiate utilization in the treatment of headache and impact on three-month outcomes following subarachnoid hemorrhage. Cureus. 2021. https://doi.org/10.7759/cureus.20773. This is a cross-sectional study covering important aspects of increased opioid use for headache management during and after hospitalization.

Cutrer MF, O’donnell A. Pathophysiology of headaches. In: Warfield CA, Bajwa ZH, editors. Principles & Practice of Pain Medicine, New York: McGraw-Hill; 2004. p. 1–9.

Chowdhury T, Garg R, Sheshadri V, Venkatraghavan L, Bergese SD, Cappellani RB, et al. Perioperative factors contributing the post-craniotomy pain: a synthesis of concepts. Front Med. 2017;4:1–5. https://doi.org/10.3389/fmed.2017.00023.

Article  Google Scholar 

•• Sorrentino ZA, Laurent D, Hernandez J, Davidson C, Small C, Dodd W, et al. Headache persisting after aneurysmal subarachnoid hemorrhage: a narrative review of pathophysiology and therapeutic strategies. Headache. 2022;62:1120–32. https://doi.org/10.1111/head.14394. This is a very comprehensive review article covering important aspects of pathophysiology to gain a broad understanding and treatment approach.

Arboix A, García-Trallero O, García-Eroles L, Massons J, Comes E, Targa C. Stroke-related headache: a clinical study in lacunar infarction. Headache. 2005;45:1345–52. https://doi.org/10.1111/j.1526-4610.2005.00267.x.

Article  PubMed  Google Scholar 

•• Rasouli J, Watson C, Yaeger K, Ladner T, Kellner C, Dangayach NS. Pain control after aneurysmal subarachnoid hemorrhage: a contemporary literature review. J Clin Neurosci. 2019;68:9–12. https://doi.org/10.1016/j.jocn.2019.07.057. This is a great contemporary literature review of pain control in subarachnoid hemorrhage which provides a valuable framework and recommendations.

Xu L, Wang W, Lai N, Tong J, Wang G, Tang D. Association between pro-inflammatory cytokines in cerebrospinal fluid and headache in patients with aneurysmal subarachnoid hemorrhage. J Neuroimmunol. 2022;366:577841. https://doi.org/10.1016/j.jneuroim.2022.577841.

Article  CAS  PubMed  Google Scholar 

Swope R, Glover K, Gokun Y, Fraser JF, Cook AM. Evaluation of headache severity after aneurysmal subarachnoid hemorrhage. Interdiscip Neurosurg. 2014;1:119–22. https://doi.org/10.1016/j.inat.2014.07.003.

Article  Google Scholar 

Leira R, Castellanos M, Älvarez-Sabín J, Diez-Tejedor E, Dávalos A, Castillo J, et al. Headache in cerebral hemorrhage is associated with inflammatory markers and higher residual cavity. Headache. 2005;45:1236–43. https://doi.org/10.1111/j.1526-4610.2005.00248.x.

Article  PubMed  Google Scholar 

Oliveira FAA, Sampaio Rocha-Filho PA. Headaches attributed to ischemic stroke and transient ischemic attack. Headache. 2019;59:469–76. https://doi.org/10.1111/head.13478.

Article  PubMed  Google Scholar 

Chen SP, Wang SJ. Pathophysiology of reversible cerebral vasoconstriction syndrome. J Biomed Sci. 2022;29:1–13. https://doi.org/10.1186/s12929-022-00857-4.

Article  CAS  Google Scholar 

Eisinger RS, Sorrentino ZA, Lucke-Wold B, Zhou S, Barlow B, Hoh B, et al. Severe headache trajectory following aneurysmal subarachnoid hemorrhage: the association with lower sodium levels. Brain Inj. 2022;36:579–85. https://doi.org/10.1080/02699052.2022.2055146.

Article  PubMed  PubMed Central  Google Scholar 

Garg R, Bar B. Systemic complications following aneurysmal subarachnoid hemorrhage. Curr Neurol Neurosci Rep. 2017;17:1–7. https://doi.org/10.1007/s11910-017-0716-3.

Article  Google Scholar 

Dorhout Mees SM, Bertens D, Van Der Worp HB, Rinkel GJE, Van Den Bergh WM. Magnesium and headache after aneurysmal subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry. 2010;81:490–3. https://doi.org/10.1136/jnnp.2009.181404.

Article  CAS  PubMed  Google Scholar 

Ashina H, Porreca F, Anderson T, Mohammad Amin F, Ashina M, Winther Schytz H, et al. Post-traumatic headache: epidemiology and pathophysiological insights. Nat Rev Neurol. 2019;15:607–17. https://doi.org/10.1038/s41582-019-0243-8.

Article  PubMed  Google Scholar 

Lin J, Zhang S, He F, Liu M, Ma X. The status of diagnosis and treatment to intracranial hypotension, including SIH. J Headache Pain. 2017;18:1–8. https://doi.org/10.1186/s10194-016-0708-8.

Article  Google Scholar 

Cruz SL, Granados-Soto V. Opioids and opiates: pharmacology, abuse, and addiction. In: Pfaff DW, Volkow ND, editors. Neuroscience in the 21st Century. New York: Springer; 2015;1–33.

Google Scholar 

• Lin N, Mandel D, Chuck CC, Kalagara R, Doelfel SR, Zhou H, et al. Risk factors for opioid utilization in patients with intracerebral hemorrhage. Neurocrit Care. 2022;36:964–73. https://doi.org/10.1007/s12028-021-01404-z. This retrospective cohort study provides a novel up-to-date description of opioid in patient and discharge prescription patterns in ICH patients and its relationship with dependence.

•• Viswanathan V, Lucke-Wold B, Jones C, Aiello G, Li Y, Ayala A, et al. Change in opioid and analgesic use for headaches after aneurysmal subarachnoid hemorrhage over time. Neurochirurgie. 2021;67:427–32. https://doi.org/10.1016/j.neuchi.2021.03.006. This article provides an excellent overview of heavy reliance on opioid usage in SAH patients, which demands attention due to the ongoing opioid crisis.

Higgins C, Smith BH, Matthews K. Incidence of iatrogenic opioid dependence or abuse in patients with pain who were exposed to opioid analgesic therapy: a systematic review and meta-analysis. Br J Anaesth. 2018;120:1335–44. https://doi.org/10.1016/j.bja.2018.03.009.

Article  CAS  PubMed  Google Scholar 

Vowles KE, McEntee ML, Julnes PS, Frohe T, Ney JP, Van Der Goes DN. Rates of opioid misuse, abuse, and addiction in chronic pain: a systematic review and data synthesis. Pain. 2015;156:569–76. https://doi.org/10.1097/01.j.pain.0000460357.01998.f1.

Article  PubMed  Google Scholar 

Brat GA, Agniel D, Beam A, Yorkgitis B, Bicket M, Homer M, et al. Postsurgical prescriptions for opioid naive patients and association with overdose and misuse: retrospective cohort study. BMJ. 2018;360:1–9. https://doi.org/10.1136/bmj.j5790.

Article  Google Scholar 

Higginbotham JA, Markovic T, Massaly N, Morón JA. Endogenous opioid systems alterations in pain and opioid use disorder. Front Syst Neurosci. 2022;16:1–24. https://doi.org/10.3389/fnsys.2022.1014768.

Article  CAS  Google Scholar 

Friedman BW, Irizarry E, Cain D, Caradonna A, Minen MT, Solorzano C, et al. Randomized study of metoclopramide plus diphenhydramine for acute posttraumatic headache. Neurology. 2021;96:E2323–31. https://doi.org/10.1212/WNL.0000000000011822.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jaadi S Al, Al-Kindi Y, Al-Saadi T. Safety of metoclopramide in traumatic brain injury patients. Indian J Neurotrauma. 2020;19:122–6. https://doi.org/10.1055/s-0040-1717213.

Arumugam S, Lau CSM, Chamberlain RS. Use of preoperative gabapentin significantly reduces postoperative opioid consumption: a meta-analysis. J Pain Res. 2016;9:631–40. https://doi.org/10.2147/JPR.S112626.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hah JM, Bateman BT, Ratliff J, Curtin C, Sun E. Chronic opioid use after surgery: implications for perioperative management in the face of the opioid epidemic. Anesth Analg. 2017;125:1733–40. https://doi.org/10.1213/ANE.0000000000002458.

Article  PubMed  PubMed Central  Google Scholar 

Gaastra B, Carmichael H, Galea I, Bulters D. Duration and characteristics of persistent headache following aneurysmal subarachnoid hemorrhage. Headache. 2022;62:1376–82. https://doi.org/10.1111/head.14418.

Article  PubMed  PubMed Central  Google Scholar 

Huckhagel T, Klinger R, Schmidt NO, Regelsberger J, Westphal M, Czorlich P. The burden of headache following aneurysmal subarachnoid hemorrhage: a prospective single-center cross-sectional analysis. Acta Neurochir. 2020;162:893–903. https://doi.org/10.1007/s00701-020-04235-7.

Article  PubMed  Google Scholar 

• Smith CR, Fox WC, Robinson CP, Garvan C, Babi MA, Pizzi MA, et al. Pterygopalatine fossa blockade as novel, narcotic-sparing treatment for headache in patients with spontaneous subarachnoid hemorrhage. Neurocrit Care. 2021;35:241–8. https://doi.org/10.1007/s12028-020-01157-1. This is an auspicious and novel case series treatment approach for pain treatment in SAH patients. This promising opioid-sparing therapeutic strategy is currently being addressed in a randomized controlled trial.

Morotti A, Goldstein JN. Diagnosis and management of acute intracerebral hemorrhage. Emerg Med Clin North Am. 2016;34:883–99. https://doi.org/10.1016/j.emc.2016.06.010.

Article  PubMed  PubMed Central  Google Scholar 

Ribas MZ, Paticcié GF, de Medeiros SDP, de Oliveira VA, Noleto FM, dos Santos JCC. Reversible cerebral vasoconstriction syndrome: literature review. Egypt J Neurol Psychiatr Neurosurg. 2023;59:5. https://doi.org/10.1186/s41983-023-00607-9.

Article  PubMed  PubMed Central  Google Scholar 

Jafari S, Albin C, Izzy S. Cerebral Venous Thrombosis. In: Fawaz A-M, Krishna A, editors. Cerebrovascular disorders. New York: Humana Press; 2021;379–94.

Chapter  Google Scholar 

• Ashina H, Al-Khazali HM, Iljazi A, Ashina S, Amin FM, Schytz HW. Total tenderness score and pressure pain thresholds in persistent post-traumatic headache attributed to mild traumatic brain injury. J Headache Pain. 2022;23:1–8. https://doi.org/10.1186/s10194-022-01457-1. This study provides a novel understanding of the pathophysiology of headache in patients with persistent post-traumatic headache. It provides a broad framework for a frequent pathology among population.

Lew HL, Lin PH, Fuh JL, Wang SJ, Clark DJ, Walker WC. Characteristics and treatment of headache after traumatic brain injury: a focused review. Am J Phys Med Rehabil. 2006;85:619–27. https://doi.org/10.1097/01.phm.0000223235.09931.c0.

Article  PubMed  Google Scholar 

Olesen J, Bes A, Kunkel R, Lance JW, Nappi G, Pfaffenrath V, et al. The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia. 2013;33:629–808. https://doi.org/10.1177/0333102413485658.

Lutman B, Bloom J, Nussenblatt B, Romo V. A contemporary perspective on the management of post-craniotomy headache and pain. Curr Pain Headache Rep. 2018;22:1–7. https://doi.org/10.1007/s11916-018-0722-4.

Article  Google Scholar 

Pajor MJ, Long B, Koyfman A, Liang SY. High risk and low prevalence diseases: adult bacterial meningitis. Am J Emerg Med. 2023;65:76–83. https://doi.org/10.1016/j.ajem.2022.12.042.

Article  PubMed  Google Scholar 

Kohil A, Jemmieh S, Smatti MK, Yassine HM. Viral meningitis: an overview. Arch Virol. 2021;166:335–45. https://doi.org/10.1007/s00705-020-04891-1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kumar S, Verma R, Garg RK, Malhotra HS, Sharma PK. Prevalence and outcome of headache in tuberculous meningitis. Neurosciences. 2016;21:138–44. https://doi.or