*Chinese PLA Medical School, Beijing, China; and

†Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, Beijing, China.

Correspondence: Yundai Chen, MD, Senior Department of Cardiology, the Sixth Medical Center of PLA General Hospital, Beijing, China 100853 (e-mail: [email protected]).

This work received financial support from the National Natural Science Foundation of China (81827808, 81800221, 81970443 and 81870178).

The authors report no conflicts of interest.

R. Chen: Conceptualization, Methodology, Investigation, Visualization, Writing–original draft. Y. Zhang: Methodology, Visualization, Writing–original draft. H. Zhou: Methodology, Writing, reviewing, and editing. Y. Hu: Methodology, Writing, reviewing, and editing. Y. Chen: Conceptualization, Investigation, Supervision, Writing the original draft. All authors have contributed to the manuscript and approved the submitted version.

The data that support the findings of this study are available in the Methods section of this study.

R. Chen and Y. Zhang have contributed equally.