Efficacy of virtual reality training on motor performance, activity of daily living, and quality of life in patients with Parkinson's disease: an umbrella review comprising meta-analyses of randomized controlled trials

Simon DK, Tanner CM, Brundin P. Parkinson disease epidemiology, pathology, genetics, and pathophysiology. Clin Geriatr Med. 2020;36(1):1–12. https://doi.org/10.1016/j.cger.2019.08.002.

Article  PubMed  Google Scholar 

Tysnes O, Storstein A. Epidemiology of Parkinson’s disease. J Neural Transm (Vienna, Austria: 1996). 2017;124(8):901–5. https://doi.org/10.1007/s00702-017-1686-y.

Article  Google Scholar 

Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, et al. Mds clinical diagnostic criteria for Parkinson’s disease. Mov Disord. 2015;30(12):1591–601. https://doi.org/10.1002/mds.26424.

Article  PubMed  Google Scholar 

Vijiaratnam N, Simuni T, Bandmann O, Morris HR, Foltynie T. Progress towards therapies for disease modification in Parkinson’s disease. Lancet Neurol. 2021;20(7):559–72. https://doi.org/10.1016/S1474-4422(21)00061-2.

Article  CAS  PubMed  Google Scholar 

Hvingelby VS, Glud AN, Sørensen JCH, Tai Y, Andersen ASM, Johnsen E, et al. Interventions to improve gait in Parkinson’s disease: a systematic review of randomized controlled trials and network meta-analysis. J Neurol. 2022;269(8):4068–79. https://doi.org/10.1007/s00415-022-11091-1.

Article  PubMed  Google Scholar 

Wu J, Chen Z, Zheng K, Huang W, Liu F, Lin J, et al. Benefits of exergame training for female patients with fibromyalgia: a systematic review and meta-analysis of randomized controlled trials. Arch Phys Med Rehabil. 2022;103(6):1192–200. https://doi.org/10.1016/j.apmr.2021.10.022.

Article  PubMed  Google Scholar 

Henderson A, Korner-Bitensky N, Levin M. Virtual reality in stroke rehabilitation: a systematic review of its effectiveness for upper limb motor recovery. Top Stroke Rehabil. 2007;14(2):52–61. https://doi.org/10.1310/tsr1402-52.

Article  PubMed  Google Scholar 

Kim JI, Li SN, Chen XB, Keung C, Suh M, Kim TW. Evaluation framework for bim-based VR applications in design phase. J Comput Des Eng. 2021;8(3):910–22. https://doi.org/10.1093/jcde/qwab022.

Article  Google Scholar 

Li K, Wang S. Development and application of vr course resources based on embedded system in open education. Microprocess Microsy. 2021 (prepublish).

Wali A, Lisan A, Ather H, Qasim M, Abid MU. Application in multimedia: from camera to vr. Multimed Tools Appl. https://doi.org/10.1007/s11042-022-13687-1

Triegaardt J, Han TS, Sada C, Sharma S, Sharma P. The role of virtual reality on outcomes in rehabilitation of Parkinson’s disease: meta-analysis and systematic review in 1031 participants. Neurol Sci. 2020;41(3):529–36. https://doi.org/10.1007/s10072-019-04144-3.

Article  PubMed  Google Scholar 

Canning CG, Allen NE, Nackaerts E, Paul SS, Nieuwboer A, Gilat M. Virtual reality in research and rehabilitation of gait and balance in Parkinson disease. Nat Rev Neurol. 2020;16(8):409–25. https://doi.org/10.1038/s41582-020-0370-2.

Article  PubMed  Google Scholar 

Wu J, Sun Y, Zhang G, Zhou Z, Ren Z. Virtual reality-assisted cognitive behavioral therapy for anxiety disorders: a systematic review and meta-analysis. Front Psychiatry. 2021;12: 575094. https://doi.org/10.3389/fpsyt.2021.575094.

Article  PubMed  PubMed Central  Google Scholar 

Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the prisma statement. BMJ. 2009;339: b2535. https://doi.org/10.1136/bmj.b2535.

Article  PubMed  PubMed Central  Google Scholar 

Ioannidis JP. Integration of evidence from multiple meta-analyses: a primer on umbrella reviews, treatment networks and multiple treatments meta-analyses. CMAJ. 2009;181(8):488–93. https://doi.org/10.1503/cmaj.081086.

Article  PubMed  PubMed Central  Google Scholar 

Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, et al. Amstar 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ. 2017;358: j4008. https://doi.org/10.1136/bmj.j4008.

Article  PubMed  PubMed Central  Google Scholar 

Langendam MW, Akl EA, Dahm P, Glasziou P, Guyatt G, Schunemann HJ. Assessing and presenting summaries of evidence in cochrane reviews. Syst Rev. 2013;2:81. https://doi.org/10.1186/2046-4053-2-81.

Article  PubMed  PubMed Central  Google Scholar 

Higgins JP, Thompson SG, Spiegelhalter DJ. A re-evaluation of random-effects meta-analysis. J R Stat Soc Ser A Stat Soc. 2009;172(1):137–59. https://doi.org/10.1111/j.1467-985X.2008.00552.x.

Article  PubMed  PubMed Central  Google Scholar 

Riley RD, Higgins JP, Deeks JJ. Interpretation of random effects meta-analyses. BMJ. 2011;342: d549. https://doi.org/10.1136/bmj.d549.

Article  PubMed  Google Scholar 

Egger M, Davey SG, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–34. https://doi.org/10.1136/bmj.315.7109.629.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ioannidis JP, Trikalinos TA. An exploratory test for an excess of significant findings. Clin Trials. 2007;4(3):245–53. https://doi.org/10.1177/1740774507079441.

Article  PubMed  Google Scholar 

Dechartres A, Altman DG, Trinquart L, Boutron I, Ravaud P. Association between analytic strategy and estimates of treatment outcomes in meta-analyses. JAMA. 2014;312(6):623–30. https://doi.org/10.1001/jama.2014.8166.

Article  CAS  PubMed  Google Scholar 

Brabaharan S, Veettil SK, Kaiser JE, Raja RV, Wattanayingcharoenchai R, Maharajan M, et al. Association of hormonal contraceptive use with adverse health outcomes: an umbrella review of meta-analyses of randomized clinical trials and cohort studies. JAMA Netw Open. 2022;5(1): e2143730. https://doi.org/10.1001/jamanetworkopen.2021.43730.

Article  PubMed  PubMed Central  Google Scholar 

Chen Y, Gao Q, He CQ, Bian R. Effect of virtual reality on balance in individuals with Parkinson disease: a systematic review and meta-analysis of randomized controlled trials. Phys Ther. 2020;100(6):933–45. https://doi.org/10.1093/ptj/pzaa042.

Article  PubMed  Google Scholar 

Wang B, Shen M, Wang YX, He ZW, Chi SQ, Yang ZH. Effect of virtual reality on balance and gait ability in patients with Parkinson’s disease: a systematic review and meta-analysis. Clin Rehabil. 2019;33(7):1130–8. https://doi.org/10.1177/0269215519843174.

Article  PubMed  Google Scholar 

Lina C, Guoen C, Huidan W, Yingqing W, Ying C, Xiaochun C, et al. The effect of virtual reality on the ability to perform activities of daily living, balance during gait, and motor function in Parkinson disease patients: a systematic review and meta-analysis. Am J Phys Med Rehabil. 2020;99(10):917–24. https://doi.org/10.1097/PHM.0000000000001447.

Article  PubMed  Google Scholar 

Sarasso E, Gardoni A, Tettamanti A, Agosta F, Filippi M, Corbetta D. Virtual reality balance training to improve balance and mobility in Parkinson’s disease: a systematic review and meta-analysis. J Neurol. 2022;269(4):1873–88. https://doi.org/10.1007/s00415-021-10857-3.

Article  PubMed  Google Scholar 

Wang W, Wong SS, Lai FH. The effect of virtual reality rehabilitation on balance in patients with Parkinson’s disease: a systematic review and meta-analysis. Electronics. 2021;10(9):1003. https://doi.org/10.3390/electronics10091003.

Article  Google Scholar 

Zhang J, Luximon Y, Pang MYC, Wang H. Effectiveness of exergaming-based interventions for mobility and balance performance in older adults with Parkinson’s disease: systematic review and meta-analysis of randomised controlled trials. Age Ageing. 2022. https://doi.org/10.1093/ageing/afac175.

Article  PubMed  PubMed Central  Google Scholar 

Li R, Zhang Y, Jiang Y, Wang M, Ang WHD, Lau Y. Rehabilitation training based on virtual reality for patients with Parkinson’s disease in improving balance, quality of life, activities of daily living, and depressive symptoms: a systematic review and meta-regression analysis. Clin Rehabil. 2021;35(8):1089–102. https://doi.org/10.1177/0269215521995179.

Article  PubMed  Google Scholar 

Wang B, Shen M, Wang Y, He Z, Chi S, Yang Z. Effect of virtual reality on balance and gait ability in patients with Parkinson’s disease: a systematic review and meta-analysis. Clin Rehabil. 2019;33(7):1130–8. https://doi.org/10.1177/0269215519843174.

Article  PubMed  Google Scholar 

Lina C, Guoen C, Huidan W, Yingqing W, Ying C, Xiaochun C, et al. The effect of virtual reality on the ability to perform activities of daily living, balance during gait, and motor function in parkinson disease patients. Am J Phys Med Rehab. 2020;99(10):917–24. https://doi.org/10.1097/PHM.0000000000001447.

Article  Google Scholar 

Wu J, Zeng A, Chen Z, Wei Y, Huang K, Chen J, et al. Effects of virtual reality training on upper limb function and balance in stroke patients: systematic review and meta-meta-analysis. J Med Internet Res. 2021;23(10): e31051. https://doi.org/10.2196/31051.

Article  PubMed  PubMed Central  Google Scholar 

Jang SH, You SH, Hallett M, Cho YW, Park C, Cho S, et al. Cortical reorganization and associated functional motor recovery after virtual reality in patients with chronic stroke: an experimenter-blind preliminary study. 2005; p. 2218–23.

Schoene D, Heller C, Aung YN, Sieber CC, Kemmler W, Freiberger E. A systematic review on the influence of fear of falling on quality of life in older people: is there a role for falls? Clin Interv Aging. 2019;14:701–19. https://doi.org/10.2147/CIA.S197857.

Article  PubMed  PubMed Central  Google Scholar 

Hou Y, Liu Y, Li M, Ning B, Wen Z, Fu W. Acupuncture plus rehabilitation for unilateral neglect after stroke: a systematic review and meta-analysis. Evid Based Complement Altern Med eCAM. 2020;2020:5301568. https://doi.org/10.1155/2020/5301568.

Article  Google Scholar 

Wu J, Zhang H, Chen Z, Fu R, Yang H, Zeng H, et al. Benefits of virtual reality balance training for patients with parkinson disease: systematic review, meta-analysis, and meta-regression of a randomized controlled trial. Jmir Serious Games. 2022;10(1): e30882. https://doi.org/10.2196/30882.

Article  PubMed  PubMed Central 

Comments (0)

No login
gif