Document Type : Original Article

Authors

1 Isfahan University of Medical Sciences

2 MD,Associate Professor, Division of pediatrics, Neonatology Specialist, Isfahan University of Medical Sciences, Isfahan, Iran

3 Child Growth and Development Research Center, Research Institute for Primordial Prevention of Noncommunicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran

4 Department of Pediatrics, Division of Neonatology, Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

10.22038/ijn.2023.73589.2421

Abstract

Introduction: N-CPAP is the standard method of respiratory support in neonatal intensive care units, and almost all infants with respiratory distress syndrome (RDS) use this method for respiratory support. The position of infants under N-CPAP (prone and supine) affects the amount of blood supply.

Method: This randomized clinical trial was conducted on 127 premature infants under N-CPAP in the neonatal intensive care unit of Al-Zahra and Shahid Beheshti hospitals in Isfahan. Babies were placed in two groups of 68 and 59 people with supine and prone positions, respectively. The duration of N-CPAP, the number of prescribed doses of surfactant, the need for mechanical ventilation, Time to full feed and Positive end-expiratory pressure (PEEP) were investigated. The data of this study were analyzed with SPSS V22 statistical software.

Result: Mean (SD) of gestational age and birth weight of the neonates were 31.88(1.30) weeks and 1672.40(443.67) gram, respectively. Frequency of using different modes of mechanical ventilation was significantly lower in prone position group than supine position group ((17% vs. 32.4%), X2(3, N=127) =7.95, P<0.05). There was a significant correlation between position and using mechanical ventilation during the first 72hours (p=0.04, Correlation Coefficient=0.182). Multivariate analysis indicated that there is a significant correlation between position and mean time of PEEP (P<0.001, F=13.67), mean of surfactant use (P=0.013, F=6.38) and time to full feed (P=0.002, F=10.29).

Conclusion: The results of this study showed that placing preterm infants with RDS who are treated with N-CPAP in the prone position reduces complications related to being preterm or using N-CPAP.

Keywords