Kelm-Nelson CA, Lechner SA, Lettenberger SE, Kaldenberg TAR, Pahapill NK, Regenbaum A, Ciucci MR Pink1−/− rats are a useful tool to study early Parkinson disease. Brain Commun. 2021; 3: fcab077, https://doi.org/10.1093/braincomms/fcab077.
Armstrong MJ, Okun MS. Diagnosis and treatment of parkinson disease: a review. JAMA—J Am Med Assoc. 2020;323:548–60. https://doi.org/10.1001/jama.2019.22360.
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, et al. MDS clinical diagnostic criteria for Parkinson’s disease. Mov Disord. 2015;30:1591–601. https://doi.org/10.1002/mds.26424.
Sioka C, Fotopoulos A, Kyritsis AP. Recent advances in PET imaging for evaluation of Parkinson’s disease. Eur J Nucl Med Mol Imaging. 2010;37:1594–603. https://doi.org/10.1007/s00259-009-1357-9.
Savica R, Carlin JM, Grossardt BR, Bower JH, Ahlskog JE, Maraganore DM, Bharucha AE, Rocca WA. Medical records documentation of constipation preceding Parkinson disease: a case-control study. Neurology. 2009;73:1752–8. https://doi.org/10.1212/WNL.0b013e3181c34af5.
Article CAS PubMed PubMed Central Google Scholar
Gao X, Chen H, Schwarzschild MA, Ascherio A. A prospective study of bowel movement frequency and risk of parkinson’s disease. Am J Epidemiol. 2011;174:546–51. https://doi.org/10.1093/aje/kwr119.
Article PubMed PubMed Central Google Scholar
O’Sullivan SS, Williams DR, Gallagher DA, Massey LA, Silveira-Moriyama L, Lees AJ. Nonmotor symptoms as presenting complaints in Parkinson’s disease: a clinicopathological study. Mov Disord. 2008;23:101–6. https://doi.org/10.1002/mds.21813.
Suttrup I, Warnecke T. Dysphagia in Parkinson’s disease. Dysphagia. 2016;31:24–32. https://doi.org/10.1007/s00455-015-9671-9.
Kashihara K Weight loss in Parkinson’s disease. J Neurol. 2006; 2537: 2006, 253, vii38–vii41, https://doi.org/10.1007/S00415-006-7009-0.
Findley LJ. The economic impact of Parkinson’s disease. Park Relat Disord. 2007;13:S8–12. https://doi.org/10.1016/j.parkreldis.2007.06.003.
Farri A, Accornero A, Burdese C. Social importance of dysphagia: its impact on diagnosis and therapy. Acta Otorhinolaryngol Ital. 2007;27:83–6.
CAS PubMed PubMed Central Google Scholar
Plowman-Prine EK, Sapienza CM, Okun MS, Pollock SL, Jacobson C, Wu SS, Rosenbek JC. The relationship between quality of life and swallowing in Parkinson’s disease. Mov Disord. 2009;24:1352–8. https://doi.org/10.1002/mds.22617.
Article PubMed PubMed Central Google Scholar
Kwon M, Lee J-H. Oro-pharyngeal dysphagia in Parkinson’s disease and related movement disorders. J Mov Disord. 2019;12:152–60. https://doi.org/10.14802/jmd.19048.
Article PubMed PubMed Central Google Scholar
Tjaden K. Speech and swallowing in Parkinsonʼs disease. Top Geriatr Rehabil. 2008;24:115–26. https://doi.org/10.1097/01.TGR.0000318899.87690.44.
Article PubMed PubMed Central Google Scholar
Kalf JG, de Swart BJM, Bloem BR, Munneke M. Prevalence of oropharyngeal dysphagia in Parkinson’s disease: a meta-analysis. Parkinsonism Relat Disord. 2012;18:311–5. https://doi.org/10.1016/j.parkreldis.2011.11.006.
Article CAS PubMed Google Scholar
Singer RB. Mortality in patients with Parkinson’s disease treated with dopa. J Insur Med. 1992;24:126–7.
Gorell JM, Johnson CC, Rybicki BA. Parkinson’s disease and its comorbid disorders: an analysis of Michigan mortality data, 1970 to 1990. Neurology. 1994;44:1865–8. https://doi.org/10.1212/wnl.44.10.1865.
Article CAS PubMed Google Scholar
Fernandez HH, Lapane KL Predictors of mortality among nursing home residents with a diagnosis of Parkinson’s disease. Med Sci Monit. 2002; 8: CR241–6.
Troche MS, Okun MS, Rosenbek JC, Musson N, Fernandez HH, Rodriguez R, Romrell J, Pitts T, Wheeler-Hegland KM, Sapienza CM. Aspiration and swallowing in Parkinson disease and rehabilitation with EMST: a randomized trial. Neurology. 2010;75:1912–9. https://doi.org/10.1212/WNL.0b013e3181fef115.
Article CAS PubMed PubMed Central Google Scholar
Curtis JA, Molfenter S, Troche MS. Predictors of residue and airway invasion in Parkinson’s disease. Dysphagia. 2020;35:220–30. https://doi.org/10.1007/s00455-019-10014-z.
Mukherjee A, Biswas A, Das SK. Gut dysfunction in Parkinson’s disease. World J Gastroenterol. 2016;22:5742–52. https://doi.org/10.3748/wjg.v22.i25.5742.
Article CAS PubMed PubMed Central Google Scholar
Przuntek H, Müller T, Riederer P Diagnostic staging of Parkinson’s disease: conceptual aspects. J Neural Transm 2004; 1112 2004; 111, 201–216, https://doi.org/10.1007/S00702-003-0102-Y.
Poewe W. Non-motor symptoms in Parkinson’s disease. Eur J Neurol. 2008;15:14–20. https://doi.org/10.1111/j.1468-1331.2008.02056.x.
Fasano A, Visanji NP, Liu LWC, Lang AE, Pfeiffer RF. Gastrointestinal dysfunction in Parkinson’s disease. Lancet Neurol. 2015;14:625–39. https://doi.org/10.1016/S1474-4422(15)00007-1.
Article CAS PubMed Google Scholar
Hatano Y, Li Y, Sato K, Asakawa S, Yamamura Y, Tomiyama H, Yoshino H, Asahina M, Kobayashi S, Hassin-Baer S, et al. Novel PINK1 mutations in early-onset parkinsonism. Ann Neurol. 2004;56:424–7. https://doi.org/10.1002/ana.20251.
Article CAS PubMed Google Scholar
Li Y, Tomiyama H, Sato K, Hatano Y, Yoshino H, Atsumi M, Kitaguchi M, Sasaki S, Kawaguchi S, Miyajima H, et al. Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism. Neurology. 2005;64:1955–7. https://doi.org/10.1212/01.WNL.0000164009.36740.4E.
Article CAS PubMed Google Scholar
Dave KD, De Silva S, Sheth NP, Ramboz S, Beck MJ, Quang C, Switzer RC, Ahmad SO, Sunkin SM, Walker D, et al. Phenotypic characterization of recessive gene knockout rat models of Parkinson’s disease. Neurobiol Dis. 2014;70:190–203. https://doi.org/10.1016/j.nbd.2014.06.009.
Article CAS PubMed Google Scholar
Yang KM, Blue KV, Mulholland HM, Kurup MP, Kelm-Nelson CA, Ciucci MR. Characterization of oromotor and limb motor dysfunction in the DJ1 -/- model of Parkinson disease. Behav Brain Res. 2018;339:47–56. https://doi.org/10.1016/j.bbr.2017.10.036.
Grant LM, Kelm-Nelson CA, Hilby BL, Blue KV, Paul Rajamanickam ES, Pultorak JD, Fleming SM, Ciucci MR. Evidence for early and progressive ultrasonic vocalization and oromotor deficits in a PINK1 gene knockout rat model of Parkinson’s disease. J Neurosci Res. 2015;93:1713–27. https://doi.org/10.1002/jnr.23625.
Article CAS PubMed PubMed Central Google Scholar
Krasko MN, Hoffmeister JD, Schaen-Heacock NE, Welsch JM, Kelm-Nelson CA, Ciucci MR Rat Models of Vocal Deficits in Parkinson’s Disease. Brain Sci. 2021; 11: 925 https://doi.org/10.3390/BRAINSCI11070925.
Kelm-Nelson CA, Trevino MA, Ciucci MR. Quantitative analysis of catecholamines in the Pink1 −/− rat model of early-onset Parkinson’s Disease. Neuroscience. 2018;379:126–41. https://doi.org/10.1016/j.neuroscience.2018.02.027.
Article CAS PubMed Google Scholar
Hoffmeister JD, Kelm-Nelson CA, Ciucci MR Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease. Behav. Brain Res. 2021; 414: 113514, https://doi.org/10.1016/j.bbr.2021.113514.
Glass TJ, Kelm-Nelson CA, Szot JC, Lake JM, Connor NP, Ciucci MR Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease. PLoS One 2020;15: e0240366, https://doi.org/10.1371/journal.pone.0240366.
Glass TJ, Kelm-Nelson CA, Russell JA, Szot JC, Lake JM, Connor NP, Ciucci MR. Laryngeal muscle biology in the Pink1/ rat model of Parkinson disease. J Appl Physiol. 2019;126:1326–34. https://doi.org/10.1152/japplphysiol.00557.2018.
Article CAS PubMed PubMed Central Google Scholar
Cullen KP, Grant LM, Kelm-Nelson CA, Brauer AFL, Bickelhaupt LB, Russell JA, Ciucci MR. Pink1 −/− rats show early-onset swallowing deficits and correlative brainstem pathology. Dysphagia. 2018;33:749–58. https://doi.org/10.1007/s00455-018-9896-5.
Article PubMed PubMed Central Google Scholar
Braak H, Del Tredici K, Rüb U, De Vos RAI, Jansen Steur ENH, Braak E Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging 2003; 24: 197–211, https://doi.org/10.1016/S0197-4580(02)00065-9.
Russell JA, Ciucci MR, Hammer MJ, Connor NP. Videofluorographic assessment of deglutitive behaviors in a rat model of aging and parkinson disease. Dysphagia. 2013;28:95–104. https://doi.org/10.1007/s00455-012-9417-x.
Cullins MJ, Connor NP. Reduced tongue force and functional swallowing changes in a rat model of post stroke dysphagia. Brain Res. 2019;1717:160–6. https://doi.org/10.1016/j.brainres.2019.04.023.
Article CAS PubMed PubMed Central Google Scholar
Rowe LM, Connor NP, Russell JA Respiratory-swallow coordination in a rat model of chemoradiation. Head Neck 2021, hed.26782, https://doi.org/10.1002/hed.26782.
Cabezos PA, Vera G, Castillo M, Fernández-Pujol R, Martín MI, Abalo R Radiological study of gastrointestinal motor activity after acute cisplatin in the rat. Temporal relationship with pica. Auton Neurosci Basic Clin 2008: 141: 54–65, https://doi.org/10.1016/j.autneu.2008.05.004.
Bakke M, Larsen SL, Lautrup C, Karlsborg M. Orofacial function and oral health in patients with Parkinson’s disease. Eur J Oral Sci. 2011;119:27–32. https://doi.org/10.1111/j.1600-0722.2010.00802.x.
Ali GN, Wallace KL, Schwartz R, DeCarle DJ, Zagami AS, Cook IJ. Mechanisms of oral-pharyngeal dysphagia in patients with Parkinson’s disease. Gastroenterology. 1996;110:383–92.
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