Lefever E, Vliebergh J, Mathieu C. Improving the treatment of patients with diabetes using insulin analogues: current findings and future directions. Expert Opin Drug Saf. 2021;20:155–69.

Article  CAS  PubMed  Google Scholar 

Silver B, Ramaiya K, Andrew SB, Fredrick O, Bajaj S, Kalra S, et al. EADSG guidelines: insulin therapy in diabetes. Diabetes Ther. 2018;9:449–92.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sim KH, Hwang MS, Kim SY, Lee HM, Chang JY, Lee MK. The appropriateness of the length of insulin needles based on determination of skin and subcutaneous fat thickness in the abdomen and upper arm in patients with type 2 diabetes. Diabetes Metab J. 2014;38:120–33.

Article  PubMed  PubMed Central  Google Scholar 

Lim STJ, Hui YCA, Lim PK, Lim CCE, Yen Chia Y, Vasanwala RF. Ultrasound-guided measurement of skin and subcutaneous tissue thickness in children with diabetes and recommendations for giving insulin injections. J Clin Transl Endocrinol. 2018;12:26–35.

PubMed  PubMed Central  Google Scholar 

Hirsch LJ, Strauss KW. The injection technique factor: what you don’t know or teach can make a difference. Clin Diabetes. 2019;37:227–33.

Article  PubMed  PubMed Central  Google Scholar 

Down S, Kirkland F. Injection technique in insulin therapy. Nurs Times. 2012;108:1820–1.

Google Scholar 

Gibney MA, Arce CH, Byron KJ, Hirsch LJ. Skin and subcutaneous adipose layer thickness in adults with diabetes at sites used for insulin injections; implications for needle length recommendations. Curr Med Res Opin. 2010;26:1519–30.

Article  CAS  PubMed  Google Scholar 

Lippert WC, Wall EJ. Optimal intramuscular needle-penetration depth. Pediatrics. 2008;122:e556–63.

Article  PubMed  Google Scholar 

Certification board for diabetes educators in Japan. Guidebook for diabetes educate in 2021. Tokyo: Medical review; 2021.

Google Scholar 

De Coninck C, Frid A, Gaspar R, Hicks D, Hirsch L, Kreugel G, et al. Results and analysis of the 2008–2009 Insulin Injection Technique Questionnaire survey. J Diabetes. 2010;2:168–79.

Article  PubMed  Google Scholar 

Hirsch L, Klaff L, Bailey T, Gibney M, Albanese J, Qu S, et al. Comparative glycemic control, safety and patient ratings for a new 4 mm × 32G insulin pen needle in adults with diabetes. Curr Med Res Opin. 2010;26:1531–41.

Article  CAS  PubMed  Google Scholar 

Hirsch L, Byron K, Gibney M. Intramuscular risk at insulin injection sites: measurement of the distance from skin to muscle and rationale for shorter-length needles for subcutaneous insulin therapy. Diabetes Technol Ther. 2014;16:867–73.

Article  CAS  PubMed  Google Scholar 

Kreugel G, Keers JC, Kerstens MN, Wolffenbuttel BH. Randomized trial on the influence of the length of two insulin pen needles on glycemic control and patient preference in obese patients with diabetes. Diabetes Technol Ther. 2011;13:737–41.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miwa T, Itoh R, Kobayashi T, Tanabe T, Shikuma J, Takahashi T, et al. Comparison of the effects of a new 32-gauge × 4-mm pen needle and a 32-gauge × 6-mm pen needle on glycemic control, safety, and patient ratings in Japanese adults with diabetes. Diabetes Technol Ther. 2014;14:1084–90.

Article  Google Scholar 

Nagai Y, Ohshige T, Arai K, Kobayashi H, Sada Y, Ohmori S. Comparison between shorter straight and thinner microtapered insulin injection needles. Diabetes Technol Ther. 2013;15:550–5.

Article  CAS  PubMed  Google Scholar 

Birkebaek NH, Solvig J, Hansen B, Jorgensen C, Smedegaard J, Christiansen JS. A 4-mm needle reduces the risk of intramuscular injections without increasing backflow to skin surface in lean diabetic children and adults. Diabetes Care. 2008;31:e65.

Article  PubMed  Google Scholar 

Wang W, Guo X, Shen G, Bai G, Wei Z, Liu J, et al. Skin and subcutaneous tissue thickness at insulin injection sites in Chinese diabetes patients: clinical implications. Diabetes Metabo. 2016;2042:374–7.

Article  Google Scholar 

Jain SM, Pandey K, Lahoti A, Rao PK. Evaluation of skin and subcutaneous tissue thickness at insulin injection sites in Indian, insulin naïve, type-2 diabetic adult population. Indian J Endocrinol Metab. 2013;17:864–70.

Article  PubMed  PubMed Central  Google Scholar 

Hansen B, Matytsina I. Insulin administration: selecting the appropriate needle and individualizing the injection technique. Expert Opin Drug Deliv. 2011;8:1395–406.

Article  CAS  PubMed  Google Scholar 

Jung HJ, Kim DW, Chung SL, Kim TH. A study on the skin thickness of Koreans by ultrasound. Korean J Dermatol. 1990;28:121–9.

Google Scholar 

Hauner H, Stockamp B, Haastert B. Prevalence of lipohypertrophy in insulin-treated diabetic patients and predisposing factors. Exp Clin Endocrinol Diabetes. 1996;104(2):106–10.

Article  CAS  PubMed  Google Scholar 

Gorska-Ciebiada M, Masierek M, Ciebiada M. Improved insulin injection technique, treatment satisfaction and glycemic control: results from a large cohort education study. J Clin Transl Endocrinol. 2020;4(19):100217.

Google Scholar 

Nakatani Y, Matsumura M, Monden T, Aso Y, Nakamoto T. Improvement of glycemic control by re-education in insulin technique in patients with diabetes mellitus. Adv Ther. 2013;30:897–906.

Article  CAS  PubMed  Google Scholar