Review of Intravesicular Cidofovir for BK Virus Hemorrhagic Cystitis

1.

Gilis L, Morisset S, Billaud G, Ducastelle-Leprêtre S, Labussière-Wallet H, Nicolini FE, et al. High burden of BK virus-associated hemorrhagic cystitis in patients undergoing allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplantation [Internet]. 2014;49(5):664–70 [cited 2020 Sep 13] Available from: www.nature.com/bmt.

2.

Abudayyeh A, Hamdi A, Lin H, Abdelrahim M, Rondon G, Andersson BS, et al. Symptomatic BK virus infection is associated with kidney function decline and poor overall survival in allogeneic hematopoietic stem cell recipients. American Journal of Transplantation [Internet]. 2016;16(5):1492–502 [cited 2020 Sep 13] Available from: http://doi.wiley.com/10.1111/ajt.13635.

3.

Fanourgiakis P, Georgala A, Vekemans M, Triffet A, de Bruyn J-M, Duchateau V, et al. Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient [Internet]. Vol. 40. Clin Infect Dis. 2005; [cited 2020 Sep 13]. Available from: https://www.jstor.org/stable/4484034.

4.

Hirsch HH. 2005 BK Virus: opportunity makes a pathogen [Internet]. Vol. 41. [cited 2020 Sep 13]. Available from: https://about.jstor.org/terms

5.

Hirsch HH, Steiger J. (2003) Polyomavirus BK. Vol. 3, Lancet infectious diseases. Lancet Publishing Group;. p. 611–23

6.

Bedi A, Miller CB, Hanson JL, Goodman S, Ambinder RF, Charache P, et al. Association of BK virus with failure of prophylaxis against hemorrhagic cystitis following bone marrow transplantation. J Clin Oncol. 1995;13.

7.

Arthur RR, Shah KV, Baust SJ, Santos GW, Saral R. Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplants. New England Journal of Medicine [Internet]. 1986;315(4):230–4 [cited 2020 Sep 13] Available from: http://www.nejm.org/doi/abs/10.1056/NEJM198607243150405.

CAS  Article  Google Scholar 

8.

Uhm J, Hamad N, Michelis FV, Shanavas M, Kuruvilla J, Gupta V, et al. The risk of polyomavirus BK-associated hemorrhagic cystitis after allogeneic hematopoietic SCT is associated with myeloablative conditioning, CMV viremia and severe acute GVHD. In: Bone Marrow Transplantation [Internet]. Nat Publ Group. 2014:1528–34 [cited 2020 Sep 13] Available from: www.nature.com/bmt.

9.

Cesaro S, Dalianis T, Rinaldo CH, Koskenvuo M, Pegoraro A, Einsele H, et al. ECIL guidelines for the prevention, diagnosis and treatment of BK polyomavirus-associated haemorrhagic cystitis in haematopoietic stem cell transplant recipients. J Antimicrob Chemother. 2018;73(1):12–21.

10.

Erard V, Storer B, Corey L, Nollkamper J, Huang ML, Limaye A, et al. BK virus infection in hematopoietic stem cell transplant recipients: frequency, risk factors, and association with postengraftment hemorrhagic cystitis. Clin Infect Dis. 2004;39(12):1861–5.

11.

Giraud G, Priftakis P, Bogdanovic G, Remberger M, Dubrulle M, Hau A, et al. BK-viruria and haemorrhagic cystitis are more frequent in allogeneic haematopoietic stem cell transplant patients receiving full conditioning and unrelated-HLA-mismatched grafts. Bone Marrow Transplant. 2008;41(8):737–42.

12.

Silva L, De P, Patah PA, Saliba RM, Szewczyk NA, Gilman L, et al. Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplants is the complex result of BK virus infection, preparative regimen intensity and donor type. Haematologica. 2010;95(7):1183–90.

13.

Antonsson A, Green AC, Mallitt KA, O’Rourke PK, Pawlita M, Waterboer T, et al. Prevalence and stability of antibodies to the BK and JC polyomaviruses: a long-term longitudinal study of Australians. Journal of General Virology [Internet]. 2010;91(7):1849–53 [cited 2020 Oct 22] Available from: https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.020115-0.

14.

Kwak EJ, Vilchez RA, Randhawa P, Shapiro R, Butel JS, Kusne S. Pathogenesis and management of polyomavirus infection in transplant recipients [Internet]. Clin Infect Dis. 2002;35 [cited 2020 Sep 13]. Available from: https://www.jstor.org/stable/4483268.

15.

AYH L, Yuen KY, Kwong YL. Polyoma BK virus and haemorrhagic cystitis in haematopoietic stem cell transplantation: a changing paradigm. Bone Marrow Transplant. 2005;36:929–37.

Article  Google Scholar 

16.

Aldiwani M, Tharakan T, Al-Hassani A, Gibbons N, Pavlu J, Hrouda D. BK virus associated haemorrhagic cystitis. A systematic review of current prevention and treatment strategies [Internet]. Vol. 63, International Journal of Surgery. Elsevier Ltd; 2019 [cited 2020 Sep 1]. p. 34–42. Available from: https://pubmed.ncbi.nlm.nih.gov/30711618/

17.

Abudayyeh A, Hamdi A, Abdelrahim M, Lin H, Page VD, Rondon G, et al. Poor immune reconstitution is associated with symptomatic BK polyomavirus viruria in allogeneic stem cell transplant recipients. Transpl Infect Dis. 2017;19(1).

18.

Bogdanovic G, Priftakis P, Giraud G, Kuzniar M, Ferraldeschi R, Kokhaei P, et al. Association between a high BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation. J Clin Microbiol. 2004 Nov;42(11):5394–6.

19.

Rabenau HF, Preiser W, Franck S, Schwerdtfeger S, Doerr HW. Polyomavirus viruria in bone marrow transplant recipients: lack of correlation with clinical symptoms. Infection [Internet]. 2002;30(2):91–3 [cited 2020 Sep 13] Available from: https://link.springer.com/article/10.1007/s15010-002-2010-8.

CAS  Article  Google Scholar 

20.

Erard V, Kim HW, Corey L, Limaye A, Huang ML, Myerson D, et al. BK DNA viral load in plasma: evidence for an association with hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients. Blood. 2005;106(3):1130–2.

21.

Leung AYH, Suen CKM, Lie AKW, Liang RHS, Yuen KY, Kwong YL. Quantification of polyoma BK viruria in hemorrhagic cystitis complicating bone marrow transplantation. Blood. 2001;98(6):1971–8.

CAS  Article  Google Scholar 

22.

Imlay H, Xie H, Leisenring WM, Duke ER, Kimball LE, Huang ML, et al. Presentation of BK polyomavirus-associated hemorrhagic cystitis after allogeneic hematopoietic cell transplantation. Blood Advances. 2020;4(4):617–28.

23.

Leung AYH, Mak R, Lie AKW, Yuen KY, Cheng VCC, Liang R, et al. Clinicopathological features and risk factors of clinically overt haemorrhagic cystitis complicating bone marrow transplantation. Bone Marrow Transplant. 2002;29(6):509–13.

24.

Singh HK, Bubendorf L, Mihatsch MJ, Drachenberg CB, Nickeleit V. Urine cytology findings of polyomavirus infections [Internet]. Vol. 577, Advances in Experimental Medicine and Biology. Adv Exp Med Biol. 2006:201–12 [cited 2020 Sep 13] Available from: https://pubmed.ncbi.nlm.nih.gov/16626038/.

25.

Kerbauy LN, Kerbauy MN, Bautzer V, Chapchap EC, de Mattos VRP, da Rocha JDA, et al. Severe hemorrhagic cystitis caused by the BK polyomavirus is associated with decreased survival post-allogeneic hematopoietic stem cell transplantation. Transplant Infectious Disease [Internet]. 2019;21(5) [cited 2020 Sep 1] Available from: https://pubmed.ncbi.nlm.nih.gov/31054192/.

26.

Rao K V., Buie LW, Shea T, Gabriel DA, Comeau T, Irons R, Serody J, Eron B. Intravesicular cidofovir for the management of BK virus-associated cystitis. Vol. 15, Biology of Blood and Marrow Transplantation. Elsevier Inc.; 2009. p. 391–2.

27.

Mackey MC. Cidofovir Intravesicular para el Tratamiento de cistitis hemorrágica Asociada con Poliomavirus. Ann Pharmacother. 2012;46:442–6.

Article  Google Scholar 

28.

Droller MJ, Saral R, Santos G. Prevention of cyclophosphamide-induced hemorrhagic cystitis. Urology. 1982;20(3):256–8.

CAS  Article  Google Scholar 

29.

Jeffers-Francis LK, Burger-Calderon R, Webster-Cyriaque J. Effect of leflunomide, cidofovir and ciprofloxacin on replication of BKPyV in a salivary gland in vitro culture system. Antivir Res. 2015;118:46–55.

CAS  Article  Google Scholar 

30.

Focosi D, Maggi F, Pistolesi D, Benedetti E, Papineschi F, Galimberti S, et al. Hyperbaric oxygen therapy in BKV-associated hemorrhagic cystitis refractory to intravenous and intravesical cidofovir: case report and review of literature. Leuk Res. 2009;33(4):556–60.

31.

Savva-Bordalo J, Pinho Vaz C, Sousa M, Branca R, Campilho F, Resende R, et al. Clinical effectiveness of hyperbaric oxygen therapy for BK-virus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation. Bone Marrow Transplantation [Internet]. 2012;47(8):1095–8 [cited 2020 Sep 13] Available from: www.nature.com/bmt.

32.

Chen XC, Liu T, Li JJ, He C, Meng WT, Huang R. Efficacy and safety of leflunomide for the treatment of BK virus-associated hemorrhagic cystitis in allogeneic hematopoietic stem cell transplantation recipients. Acta Haematol. 2013;130(1):52–6.

CAS  Article  Google Scholar 

33.

Leung AYH, Chan MTL, Yuen KY, Cheng VCC, Chan KH, Wong CLP, et al. Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation. Clin Infect Dis. 2005;40(4):528–37.

34.

Andrei G, Snoeck R, Vandeputte M, De Clercq E. Activities of various compounds against murine and primate polyomaviruses. Antimicrobial Agents and Chemotherapy [Internet]. 1997;41(3):587–93 [cited 2020 Sep 13] Available from: http://aac.asm.org/.

CAS  Article  Google Scholar 

35.

Held TK, Biel SS, Nitsche A, Kurth A, Chen S, Gelderblom HR, et al. Treatment of BK virus-associated hemorrhagic cystitis and simultaneous CMV reactivation with cidofovir. Bone Marrow Transplantation [Internet]. 2000;26(3):347–50 [cited 2020 Sep 13] Available from: www.nature.com/bmt.

36.

Bernhoff E, Gutteberg TJ, Sandvik K, Hirsch HH, Rinaldo CH. Cidofovir Inhibits Polyomavirus BK replication in human renal tubular cells downstream of viral early gene expression. American Journal of Transplantation [Internet]. 2008;8(7):1413–22 [cited 2020 Sep 3] Available from: http://doi.wiley.com/10.1111/j.1600-6143.2008.02269.x.

CAS  Article  Google Scholar 

37.

Tooker GM, Stafford KA, Nishioka J, Badros AZ, Riedel DJ. Intravesicular cidofovir in the treatment of BK virus–associated hemorrhagic cystitis following hematopoietic stem cell transplantation. Annals of Pharmacotherapy [Internet]. 2020;54(6):547–53 [cited 2020 Sep 14] Available from: http://journals.sagepub.com/doi/10.1177/1060028019897896.

CAS  Article  Google Scholar 

38.

Mayer K, Schumacher M, Eis-Hübinger AM, Pietzonka S, Drosten C, Brossart P, Wolf D. Intravesical cidofovir application in BK virus cystitis after allogeneic hematopoetic stem cell transplantation (HSCT) is safe and highly effective [Internet]. Vol. 53, Bone Marrow Transplantation. Nature Publishing Group; 2018 [cited 2020 Sep 14]. p. 495–8. Available from: https://doi.org/10.1038/s41409-017-0044-x

39.

Coomes EA, Wolfe A, Michelis FV, Kim D, Dong H, Thyagu S, et al. Efficacy of cidofovir in treatment of BK virus–induced hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients. Biology of Blood and Marrow Transplantation. 2018;24(9):1901–5.

40.

Sakurada M, Kondo T, Umeda M, Kawabata H, Yamashita K, Takaori-Kondo A. Successful treatment with intravesical cidofovir for virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: a case report and a review of the literature. J Infect Chemother. 2016;22(7):495–500.

Article  Google Scholar 

41.

Philippe M, Ranchon F, Gilis L, Schwiertz V, Vantard N, Ader F, et al. Cidofovir in the treatment of BK virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation. 2016;22(4):723–30.

42.

Aitken SL, Zhou J, Ghantoji SS, Kontoyiannis DP, Jones RB, Tam VH, et al. Pharmacokinetics and safety of intravesicular cidofovir in allogeneic HSCT recipients. Journal of Antimicrobial Chemotherapy [Internet]. 2016;71(3):727–30 [cited 2020 Sep 14] Available from: https://academic.oup.com/jac/article/71/3/727/2363876.

43.

Ganguly N, Clough LA, DuBois LK, Mcguirk JP, Abhyankar S, Aljitawi OS, et al. Low-dose cidofovir in the treatment of symptomatic BK virus infection in patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective analysis of an algorithmic approach. Transpl Infect Dis. 2010;12(5):406–11.

44.

Buie LW, Rao KV, Epstein S, Shea TC, Comeau T, Gabriel DA, et al. Symptomatic improvement following intravesicular cidofovir for the management of BK virus associated cystitis. Blood. 2007;110(11):3007–7.

45.

Bridges B, Donegan S, Badros A. Cidofovir bladder instillation for the treatment of BK hemorrhagic cystitis after allogeneic stem cell transplantation. Am J Hematol. 2006;81(7):535–7.

Article  Google Scholar 

46.

Foster JH, Cheng WS, Nguyen NY, Krance R, Martinez C. Intravesicular cidofovir for BK hemorrhagic cystitis in pediatric patients after hematopoietic stem cell transplant. Pediatric Transplantation [Internet]. 2018;22(3) [cited 2020 Sep 1] Available from: https://pubmed.ncbi.nlm.nih.gov/29388318/.

47.

Pérez-Huertas P, Cueto-Sola M, Escobar-Cava P, Fernández-Navarro JM, Borrell-García C, Albert-Marí A, et al. BK virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation in the pediatric population. Journal of Pediatric Oncology Nursing [Internet]. 2017;34(1):13–9 [cited 2020 Sep 3] Available from: http://journals.sagepub.com/doi/10.1177/1043454216631952.

48.

Ruderfer D, Au J, Seth A, Naik S, Bocchini CE. I D W E E K 2 0 1 6 POSTER ABSTRACTS 154. BK virus epidemiology, risk factors and outcomes: a retrospective analysis of hematopoietic stem cell transplant patients at Texas Children’s Hospital. 2016; Available from: https://academic.oup.com/ofid/article-abstract/3/suppl_1/154/2636706

49.

Rascon J, Verkauskas G, Pasauliene R, Zubka V, Bilius V, Rageliene L. Intravesical cidofovir to treat BK virus-associated hemorrhagic cystitis in children after hematopoietic stem cell transplantation. Pediatr Transplant. 2015;19(4):E111–4.

Article  Google Scholar 

50.

Kwon HJ, Kang JH, Lee JW, Chung NG, Kim HK, Cho B. Treatment of BK virus-associated hemorrhagic cystitis in pediatric hematopoietic stem cell transplant recipients with cidofovir: a single-center experience. Transplant Infectious Disease [Internet]. 2013;15(6):569–74 [cited 2020 Sep 1] Available from: https://pubmed.ncbi.nlm.nih.gov/24028353/.

CAS  Article  Google Scholar 

51.

Koskenvuo M, Dumoulin A, Lautenschlager I, Auvinen E, Mannonen L, Anttila VJ, et al. BK polyomavirus-associated hemorrhagic cystitis among pediatric allogeneic bone marrow transplant recipients: treatment response and evidence for nosocomial transmission. J Clin Virol. 2013;56(1):77–81.

52.

Cesaro S, Hirsch HH, Faraci M, Owoc-Lempach J, Beltrame A, Tendas A, et al. Cidofovir for BK virus-associated hemorrhagic cystitis: a retrospective study. Clin Infect Dis. 2009;49(2):233–40.

53.

Cundy KC. Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir [Internet]. Vol. 36, Clinical Pharmacokinetics. Adis International Ltd; 1999 [cited 2020 Oct 4]. p. 127–43. Available from: https://link-springer-com.proxy-hs.researchport.umd.edu/article/10.2165/00003088-199936020-00004

54.

Lee SS, Ahn JS, Jung SH, Ahn SY, Kim JY, Jang HC, et al. Treatment of BK virus-associated hemorrhagic cystitis with low-dose intravenous cidofovir in patients undergoing allogeneic hematopoietic cell transplantation. Korean J Intern Med. 2015;30(2):212–8.

55.

Savona MR, Newton D, Frame D, Levine JE, Mineishi S, Kaul DR. Low-dose cidofovir treatment of BK virus-associated hemorrhagic cystitis in recipients of hematopoietic stem cell transplant. Bone Marrow Transplant. 2007;39(12):783–7.

CAS  Article  Google Scholar 

56.

Faraci M, Cuzzubbo D, Lanino E, di Marco E, Cirillo C, Dallorso S, et al. Low dosage cidofovir without probenecid as treatment for bk virus hamorrhagic cystitis after hemopoietic stem cell transplant. Pediatr Infect Dis J. 2009;28(1):55–7.

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