Upper extremity joint tenderness as a practical indicator for assessing presenteeism in rheumatoid arthritis patients

Abstract

Objective Rheumatoid arthritis (RA) causes chronic polyarthritis and joint dysfunction, reducing work productivity. This reduction is mainly due to presenteeism, characterized by impaired work performance despite being present at work. This study aims to investigate the impact of specific joint involvement, particularly in the upper extremities, on work disability in RA patients.

Methods Annual surveys assessing work disability were conducted among RA outpatients enrolled in the Nagahama Riumachi Cohort at Nagahama City Hospital, using the Work Productivity and Activity Impairment Questionnaire (WPAI). A multivariate regression analysis was performed to examine the cross-sectional and longitudinal associations between presenteeism and the tender joint count (TJC) in the extremities across two WPAI surveys.

Results The analysis included 201 patients, 52% of whom reported presenteeism. Cross-sectional analysis revealed a significant positive correlation between three or more TJCs of the upper extremity and presenteeism, with a regression coefficient (β) = 17.9 (95% confidence interval [CI]: 9.85–25.9). Among the joints evaluated, the sum of TJCs in the shoulder area (β = 9.55, CI: 5.39–13.7) and the fingers (β = 1.60, CI: 0.35–2.85) were significantly correlated with presenteeism. Additionally, change in presenteeism were significantly correlated with change in upper extremity TJCs (β = 1.41, CI: 0.05–2.77).

Conclusions The upper extremity TJC is strongly associated with presenteeism in RA patients. The TJC of the upper extremities serves as a valuable indicator for clinicians, helping them effectively assess a patient’s underlying work disability.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

Yes

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

The study was approved by the Ethics Committee of Nagahama City Hospital (approval number: H28-38. Physicians conducted the study after obtaining verbal and written consent from patients

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

Yes

Data Availability

If this paper is accepted, all relevant data will be included in the manuscript and its Supporting Information file.

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