Secondary infertility due to necrospermia in men with autosomal-dominant polycystic kidney disease: a report of two cases

Nishio S, Tsuchiya K, Nakatani S, Muto S, Mochizuki T, Kawano H, et al. A digest from evidence-based clinical practice guideline for polycystic kidney disease 2020. Clin Exp Nephrol. 2021;25:1292–302.

Article  PubMed  Google Scholar 

Luciano RL, Dahl NK. Extra-renal manifestations of autosomal dominant polycystic kidney disease (ADPKD): considerations for routine screening and management. Nephrol Dial Transplant. 2014;29:247–54.

Article  PubMed  Google Scholar 

Vora N, Perrone R, Bianchi DW. Reproductive issues for adults with autosomal dominant polycystic kidney disease. Am J Kidney Dis. 2008;51:307–18.

Article  PubMed  Google Scholar 

Fang S, Baker HWG. Male infertility and adult polycystic kidney disease are associated with necrospermia. Fertil Steril. 2003;79:643–4.

Article  PubMed  Google Scholar 

Belet U, Danaci M, Sarikaya S, Odabaş F, Utaş C, Tokgöz B, et al. Prevalence of epididymal, seminal vesicle, prostate, and testicular cysts in autosomal dominant polycystic kidney disease. Urology. 2002;60:138–41.

Article  PubMed  Google Scholar 

Torra R, Sarquella J, Calabia J, Martí J, Ars E, Fernández-Llama P, et al. Prevalence of cysts in seminal tract and abnormal semen parameters in patients with autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol. 2008;3:790–3.

Article  PubMed  PubMed Central  Google Scholar 

Okada H, Fujioka H, Tatsumi N, Fujisawa M, Gohji K, Arakawa S, et al. Assisted reproduction for infertile patients with 9 + 0 immotile spermatozoa associated with autosomal dominant polycystic kidney disease. Hum Reprod. 1999;14:110–3.

Article  CAS  PubMed  Google Scholar 

Meng J, Xu Y, Shen X, Liang C. A novel frameshift PKD1 mutation in a Chinese patient with autosomal dominant polycystic kidney disease and azoospermia: a case report. Exp Ther Med. 2019;17:507–11.

PubMed  Google Scholar 

Shefi S, Levron J, Nadu A, Raviv G. Male infertility associated with adult dominant polycystic kidney disease: a case series. Arch Gynecol Obstet. 2009;280:457–60.

Article  PubMed  Google Scholar 

Orhan I, Onur R, Ergin E, Koksal IT, Kadioglu A. Infertility treatment in autosomal dominant polycystic kidney disease (ADPKD)—a case report. Andrologia. 2000;32:91–3.

Article  CAS  PubMed  Google Scholar 

Hendry WF, Rickards D, Pryor JP, Baker LR. Seminal megavesicles with adult polycystic kidney disease. Hum Reprod. 1998;13:1567–9.

Article  CAS  PubMed  Google Scholar 

Mieusset R, Fauquet I, Chauveau D, Monteil L, Chassaing N, Daudin M, et al. The spectrum of renal involvement in male patients with infertility related to excretory-system abnormalities: phenotypes, genotypes, and genetic counseling. J Nephrol. 2017;30:211–8.

Article  PubMed  Google Scholar 

Boursier A, Dumont A, Boitrelle F, Prasivoravong J, Lefebvre-Khalil V, Robin G, et al. Necrozoospermia: the tree that hides the forest. Andrology. 2022;10:642–59.

Article  PubMed  Google Scholar 

Agarwal A, Sharma RK, Gupta S, Boitrelle F, Finelli R, Parekh N, et al. Sperm vitality and necrozoospermia: diagnosis, management, and results of a global survey of clinical practice. World J Mens Health. 2022;40:228–42.

Article  PubMed  Google Scholar 

Máté G, Balló A, Márk L, Czétány P, Szántó Á, Török A. Magnetic-activated cell sorting as a method to improve necrozoospermia-related asthenozoospermic samples. J Clin Med. 2022;11:2914.

Article  PubMed  PubMed Central  Google Scholar 

Li W, Liu G, Zhao X, Lu Y, Li H, Zhang H, et al. Genetic testing, ultrasonography and preimplantation genetic testing of men with autosomal dominant polycystic kidney disease in Hunan. China Andrologia. 2022;54:e14273.

CAS  PubMed  Google Scholar 

Danaci M, Akpolat T, Baştemir M, Sarikaya S, Akan H, Selçuk MB, et al. The prevalence of seminal vesicle cysts in autosomal dominant polycystic kidney disease. Nephrol Dial Transplant. 1998;13:2825–8.

Article  CAS  PubMed  Google Scholar 

Joo I, Kim SH, Cho JY. A comparison of seminal vesicle size on CT between autosomal dominant polycystic kidney disease (ADPKD) patients and normal subjects. Acta Radiol. 2010;51:569–72.

Article  PubMed  Google Scholar 

Deng T, Li X, Yao B. Metabonomic analysis of seminal plasma in necrozoospermia patients based on liquid chromatography-mass spectrometry. Transl Androl Urol. 2023;12:1101–14.

Article  PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif