Screening by Q Exactive liquid chromatography/tandem mass spectrometry identified Choline, 25-hydroxyvitamin D2, and SM(d18:0/16:1(9Z) (OH)) as biomarkers for high-grade serous ovarian cancer
Keywords
High-grade serous ovarian cancer
Q Exactive liquid chromatography/tandem mass spectrometry (LC–MS/MSQE)
Biomarker
Metabolomics
AbbreviationsHGSOC
High-grade serous ovarian cancer
LC-MS/MA, QE
Q Exactive liquid chromatography tandem mass spectrometry
OPLS-DA
Orthogonal partial least-squares-discriminant analysis
FIGO
International Federation of Colleges of Obstetricians and Gynecologists
ESI
Electrospray ionization
PCA
Principal Component analysis
HMBD
Human Metabolome Database
VIP
Variable important in projection
EOC
Epithelial ovarian cancer
© 2024 The Authors. Published by Elsevier B.V.
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