Polymorphisms and haplotypes of TOLLIP and MUC5B are associated with susceptibility and survival in patients with fibrotic hypersensitivity pneumonitis
Keywords
Hypersensitivity pneumonitis
MUC5B
TOLLIP
Genetic variants
Haplotypes
Susceptibility
Survival
Fibrosis
AbbreviationsHP
Hypersensitivity pneumonitis
ILDs
Interstitial lung diseases
fHP
Fibrotic hypersensitivity pneumonitis
IPF
Idiopathic pulmonary fibrosis
SNPs
Single nucleotide polymorphisms
TOLLIP
Toll-interacting protein
DLCO
Diffusing capacity of the lung for carbon monoxide
% pred
percentage of predicted
BAL
Bronchoalveolar lavage
RFLP
Restriction fragment length polymorphism
PCR
Polymerase chain reaction
dbSNP
Single nucleotide polymorphisms database
HRCT
High-resolution computed tomography
UIP
Usual interstitial pneumonia
TBLC
Transbronchial lung cryobiopsy
MAF
Minor allele frequency
© 2024 Sociedade Portuguesa de Pneumologia. Published by Elsevier España, S.L.U.
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