Rapid ART initiation with bictegravir/emtricitabine/tenofovir alafenamide in individuals presenting with advanced HIV disease (Rainbow study)

AIDS

Acute Immunodeficiency Syndrome

ART

Antiretroviral Therapy

BAI

Beck Anxiety Inventory

BDI

Beck Depression Inventory

BIC/FTC/TAF

Bictegravir/Emtricitabine/Tenofovir alafenamide

CDC

Center for Disease Control

DDIs

Drug-Drug Interactions

DHHS

Department of Health and Human Services

DTG/FTC/TAF

Dolutegravir/Emtricitabine/Tenofovir alafenamide

DTG/3TC

Dolutegravir/Lamivudine

eCRF

Electronic Case Report Forms

EACS

European AIDS Clinical Society

EDTA

Ethylenediaminetetraacetic acid

eGFR

estimated Glomerular Filtration Rate

ELISA

Enzyme-Linked Immunosorbent Assay

EVG/c

Elvitegravir/cobicistat

FDA

Food and Drug Administration

HDL

High-Density Lipoprotein

HIV

Human Immunodeficiency Virus

HPLC-UV

High-Performance Liquid Chromatography-Ultra Violet

IAS-USA

International Antiviral Society-USA

IGRA

Interferon Gamma Release Assay

INSTIs

Integrase Inhibitors

IRIS

Immune Reconstitution Inflammatory Syndrome

LDL

Low-Density Lipoprotein

MDRD

Modification of Diet in Renal Disease

NGS

Next Generation Sequencing

NNRTI

Non-Nucleoside Reverse Transcriptase Inhibitor

NRTIs

Nucleoside Reverse Transcriptase Inhibitors

OCT2

Organic Cation Transporter 2

OI

Opportunistic Infections

PBMCs

Peripheral Blood Mononuclear Cells

PDVF

Protocol-Defined Virological Failure

PLWH

People Living With HIV

PML

progressive multifocal leukoencephalopathy

PROs

Patient-Reported Outcomes

RAM

Resistance-Associated Mutations

SNAE

Serious Non-AIDS Defining Event

SAEs

Serious Adverse Events

TDM

Therapeutic Drug Monitoring

TDR

Transmitted Drug Resistance

WHO

world health organization

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