Abe Y, Ohsugi M, Haraguchi K, et al. 2006 LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis. FEBS Lett. 580 782–788

Article  PubMed  Google Scholar 

Bork P and Sudol M 1994 The WW domain: a signalling site in dystrophin? Trends Biochem. Sci. 19 531–533

Bui DA, Lee W, White AE, et al. 2016 Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP. Sci. Signal. 9 ra23

Chow SE, Hsu CC, Yang CT, et al. 2023 YAP co-localizes with the mitotic spindle and midbody to safeguard mitotic division in lung-cancer cells. FEBS J. 290 5704–5719

Article  PubMed  Google Scholar 

Dupont S, Morsut L, Aragona M, et al. 2011 Role of YAP/TAZ in mechanotransduction. Nature 474 179–183

Article  PubMed  Google Scholar 

Elosegui-Artola A, Andreu I, Beedle AEM, et al. 2017 Force triggers YAP nuclear entry by regulating transport across nuclear pores. Cell 171 1397–1410

Article  PubMed  Google Scholar 

Engler AJ, Sen S, Sweeney HL, et al. 2006 Matrix elasticity directs stem cell lineage specification. Cell 126 677–689

Article  PubMed  Google Scholar 

Gao R, Kalathur RKR, Coto-Llerena M, et al. 2021 YAP/TAZ and ATF4 drive resistance to Sorafenib in hepatocellular carcinoma by preventing ferroptosis. EMBO Mol. Med. 13 e14351

Article  PubMed  PubMed Central  Google Scholar 

Gokey JJ, Sridharan A, Xu Y, et al. 2018 Active epithelial Hippo signaling in idiopathic pulmonary fibrosis. JCI Insight 3 e98738

Article  PubMed  PubMed Central  Google Scholar 

Goshima G and Kimura A 2010 New look inside the spindle: microtubule-dependent microtubule generation within the spindle. Curr. Opin. Cell. Biol. 22 44–49

Article  PubMed  Google Scholar 

Halder G, Dupont S and Piccolo S 2012 Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat. Rev. Mol. Cell Biol. 13 591–600

Article  PubMed  Google Scholar 

Hansen CG, Moroishi T and Guan KL 2015a YAP and TAZ: a nexus for Hippo signaling and beyond. Trends Cell Biol. 25 499–513

Article  PubMed  PubMed Central  Google Scholar 

Hansen CG, Ng YL, Lam WL, et al. 2015b The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1. Cell Res. 25 1299–1313

Article  PubMed  PubMed Central  Google Scholar 

Huang Y, Su J, Liu J, et al. 2022 YAP Activation in promoting negative durotaxis and acral melanoma progression. Cells 11 3543

Article  PubMed  PubMed Central  Google Scholar 

Ibar C and Irvine KD 2020 Integration of Hippo-YAP signaling with metabolism. Dev. Cell 54 256–267

Article  PubMed  PubMed Central  Google Scholar 

Lee BS, Park DI, Lee DH, et al. 2017 Hippo effector YAP directly regulates the expression of PD-L1 transcripts in EGFR-TKI-resistant lung adenocarcinoma. Biochem. Biophys. Res. Commun. 491 493–499

Article  PubMed  Google Scholar 

Li H, Wu BK, Kanchwala M, et al. 2022 YAP/TAZ drives cell proliferation and tumour growth via a polyamine-eIF5A hypusination-LSD1 axis. Nat. Cell Biol. 24 373–383

Article  PubMed  PubMed Central  Google Scholar 

Luo J and Li P 2022 Context-dependent transcriptional regulations of YAP/TAZ in stem cell and differentiation. Stem Cell Res. Ther. 13 10

Article  PubMed  PubMed Central  Google Scholar 

McDonald CB, McIntosh SK, Mikles DC, et al. 2011 Biophysical analysis of binding of WW domains of the YAP2 transcriptional regulator to PPXY motifs within WBP1 and WBP2 adaptors. Biochemistry 50 9616–9627

Article  PubMed  Google Scholar 

Meng KP, Majedi FS, Thauland TJ, et al. 2020 Mechanosensing through YAP controls T cell activation and metabolism. J. Exp. Med. 217 e20200053

Article  PubMed  PubMed Central  Google Scholar 

Oegema K and Hyman AA 2006 Cell division; in WormBook: The online review of C. elegans biology (Pasadena (CA): WormBook)

Oka T, Mazack V and Sudol M 2008 Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J. Biol. Chem. 283 27534–27546

Article  PubMed  Google Scholar 

Panciera T, Azzolin L, Cordenonsi M, et al. 2017 Mechanobiology of YAP and TAZ in physiology and disease. Nat. Rev. Mol. Cell Biol. 18 758–770

Article  PubMed  PubMed Central  Google Scholar 

Panciera T, Azzolin L, Fujimura A, et al. 2016 Induction of expandable tissue-specific stem/progenitor cells through transient expression of YAP/TAZ. Cell Stem Cell 19 725–737

Article  PubMed  PubMed Central  Google Scholar 

Piccolo S, Dupont S and Cordenonsi M 2014 The biology of YAP/TAZ: Hippo signaling and beyond. Physiol. Rev. 94 1287–1312

Article  PubMed  Google Scholar 

Pocaterra A, Romani P and Dupont S 2020 YAP/TAZ functions and their regulation at a glance. J. Cell. Sci. 133 jcs230425

Qiao Y, Chen J, Lim YB, et al. 2017 YAP regulates actin dynamics through ARHGAP29 and promotes metastasis. Cell Rep. 19 1495–1502

Article  PubMed  Google Scholar 

Sladitschek-Martens HL, Guarnieri A, Brumana G, et al. 2022 YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS-STING. Nature 607 790–798

Article  PubMed  PubMed Central  Google Scholar 

Sorrentino G, Ruggeri N, Specchia V, et al. 2014 Metabolic control of YAP and TAZ by the mevalonate pathway. Nat. Cell Biol. 16 357–366

Article  PubMed  Google Scholar 

Sudol M 1996 Structure and function of the WW domain. Prog. Biophys. Mol. Biol. 65 113–132

Article  PubMed  Google Scholar 

Sudol M, Shields DC and Farooq A 2012 Structures of YAP protein domains reveal promising targets for development of new cancer drugs. Semin. Cell Dev. Biol. 23 827–833

Article  PubMed  PubMed Central  Google Scholar 

Totaro A, Castellan M, Battilana G, et al. 2017 YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate. Nat. Commun. 8 15206

Article  PubMed  PubMed Central  Google Scholar 

Totaro A, Castellan M, Di Biagio D, et al. 2018a Crosstalk between YAP/TAZ and Notch signaling. Trends Cell Biol. 28 560–573

Article  PubMed  PubMed Central  Google Scholar 

Totaro A, Panciera T and Piccolo S 2018b YAP/TAZ upstream signals and downstream responses. Nat. Cell Biol. 20 888–899

Article  PubMed  PubMed Central  Google Scholar 

Varelas X, Samavarchi-Tehrani P, Narimatsu M, et al. 2010 The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev. Cell 19 831–844

Article  PubMed  Google Scholar 

Vasquez RJ, Howell B, Yvon AM, et al. 1997 Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol. Biol. Cell 8 973–985

Article  PubMed  PubMed Central  Google Scholar 

Vicente JJ and Wordeman L 2019 The quantification and regulation of microtubule dynamics in the mitotic spindle. Curr. Opin. Cell Biol. 60 36–43

Article  PubMed  PubMed Central  Google Scholar 

Xia P, Gutl D, Zheden V, et al. 2019 Lateral inhibition in cell specification mediated by mechanical signals modulating TAZ activity. Cell 176 1379–1392

Article  PubMed